An Embedding-Based Approach to Repairing OWL Ontologies

High-quality ontologies are critical to ontology-based applications, such as natural language understanding and information extraction, but logical conflicts naturally occur in the lifecycle of ontology development.To deal with such conflicts, conflict detection and ontology repair become two critical tasks, and we focus on repairing ontologies.Mos

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Integrating Conformational Dynamics and Perturbation-Based Network Modeling for Mutational Profiling of Binding and Allostery in the SARS-CoV-2 Spike Variant Complexes with Antibodies: Balancing Local and Global Determinants of Mutational Escape Mechanisms

In this study, we combined all-atom MD simulations, the ensemble-based mutational scanning of protein stability and binding, and perturbation-based network profiling of allosteric interactions in the SARS-CoV-2 spike complexes with a panel of cross-reactive and ultra-potent single antibodies (B1-182.1 and A23-58.1) as well as antibody combinations

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Strengthening, rehabilitation and widening of the existing arch bridge on national route 7 over the Olifants River, South Africa

This paper describes the rehabilitation of the existing bridge over the Olifants River.The bridge is on National Route 7 near Klawer and dates back to 1957.The defining feature of Matchy Match this elegant bridge is a concrete arch spanning 92.7 m.The existing bridge displayed extensive cracking, failed expansion joints and spall damage to beam sof

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Preschoolers prefer to learn causal information

Young children, in general, appear to have a strong drive to explore the environment Salad Bars in ways that reveal its underlying causal structure.But are they really attuned specifically to casual information in this quest for understanding, or do they show equal interest in other types of non-obvious information about the world? To answer this q

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